ITGB5
integrin subunit beta 5
Summary
This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin. [provided by RefSeq, Aug 2017]
Known Variants60 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2675 | 3:124,482,113 | T/G | 3 prime UTR variant | — |
| rs2481651853 | 3:124,482,513 | G/A | — | uncertain significance |
| rs747190001 | 3:124,483,249 | G/A | — | uncertain significance |
| rs771299105 | 3:124,483,252 | C/T | — | uncertain significance |
| rs765257650 | 3:124,483,264 | C/T | — | uncertain significance |
| rs199862649 | 3:124,483,265 | G/T | — | uncertain significance |
| rs145232294 | 3:124,483,384 | C/T | — | uncertain significance |
| rs767153232 | 3:124,483,392 | G/C | — | uncertain significance |
| rs3772813 | 3:124,484,073 | T/C | intron variant | — |
| rs1877567 | 3:124,484,429 | G/T | intron variant | — |
| rs2481684816 | 3:124,487,924 | T/A | — | uncertain significance |
| rs772207772 | 3:124,492,729 | T/C | — | uncertain significance |
| rs367590881 | 3:124,492,739 | C/T | — | uncertain significance |
| rs138418397 | 3:124,494,062 | C/A | intron variant | — |
| rs6787433 | 3:124,500,787 | G/A | regulatory region variant | — |
| rs1445316857 | 3:124,515,273 | T/C | — | uncertain significance |
| rs61736434 | 3:124,515,354 | C/T | — | uncertain significance |
| rs990404433 | 3:124,515,360 | C/T | — | uncertain significance |
| rs574951402 | 3:124,515,388 | G/A | — | uncertain significance |
| rs924784211 | 3:124,515,433 | C/T | — | uncertain significance |
| rs146544547 | 3:124,515,454 | C/T | missense variant | — |
| rs1456364848 | 3:124,515,580 | G/A | — | uncertain significance |
| rs143014257 | 3:124,515,589 | C/T | — | uncertain significance |
| rs141196770 | 3:124,515,623 | G/C | — | uncertain significance |
| rs981443715 | 3:124,515,645 | A/G | — | uncertain significance |
| rs185447638 | 3:124,526,716 | G/A | intron variant | — |
| rs369922990 | 3:124,527,879 | A/G | — | uncertain significance |
| rs769809752 | 3:124,527,996 | C/T | — | uncertain significance |
| rs1579244446 | 3:124,536,497 | T/C | — | uncertain significance |
| rs780151554 | 3:124,536,511 | C/T | — | uncertain significance |
| rs758722720 | 3:124,538,621 | A/C | — | uncertain significance |
| rs2064671306 | 3:124,538,646 | C/A | — | uncertain significance |
| rs746846830 | 3:124,538,652 | C/G | — | uncertain significance |
| rs374228381 | 3:124,540,213 | C/T | — | uncertain significance |
| rs2065008874 | 3:124,560,265 | C/A | — | uncertain significance |
| rs201926531 | 3:124,560,289 | G/A | — | uncertain significance |
| rs1010098744 | 3:124,560,335 | G/C | — | uncertain significance |
| rs760641795 | 3:124,560,358 | G/A | — | uncertain significance |
| rs1296217981 | 3:124,560,363 | C/T | — | uncertain significance |
| rs144080564 | 3:124,567,165 | G/A | — | uncertain significance |
| rs140879513 | 3:124,567,207 | A/G | — | uncertain significance |
| rs142682013 | 3:124,567,210 | T/C | — | uncertain significance |
| rs763152452 | 3:124,567,241 | G/A | — | uncertain significance |
| rs755220572 | 3:124,567,294 | C/T | — | uncertain significance |
| rs61757101 | 3:124,567,347 | T/C | — | benign |
| rs760168729 | 3:124,567,364 | C/T | — | uncertain significance |
| rs28372859 | 3:124,567,399 | T/A | — | uncertain significance |
| rs10934693 | 3:124,573,826 | G/A | — | — |
| rs11928547 | 3:124,577,290 | T/G | — | — |
| rs767939320 | 3:124,578,094 | C/T | — | uncertain significance |
| rs141786908 | 3:124,578,121 | G/A | — | uncertain significance |
| rs1209975008 | 3:124,578,190 | T/G | — | uncertain significance |
| rs112151655 | 3:124,578,212 | C/G | — | likely benign |
| rs149343492 | 3:124,578,268 | G/A | — | uncertain significance |
| rs771204149 | 3:124,578,287 | C/T | — | uncertain significance |
| rs753723289 | 3:124,592,335 | T/A | — | uncertain significance |
| rs1433598678 | 3:124,592,352 | C/A | — | uncertain significance |
| rs9875516 | 3:124,598,026 | A/T | regulatory region variant | — |
| rs62265658 | 3:124,599,401 | C/T | intron variant | — |
| rs1007856 | 3:124,604,858 | A/G | regulatory region variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.