KDM1B

lysine demethylase 1B

Summary

Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (Karytinos et al., 2009 [PubMed 19407342]).[supplied by OMIM, Oct 2009]

Known Variants26 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs551155433	6:18,158,563	A/T	—	—
rs2534076962	6:18,160,206	G/C	—	uncertain significance
rs148087354	6:18,161,559	C/T	—	uncertain significance
rs115866051	6:18,161,574	C/T	—	likely benign
rs140118994	6:18,161,579	A/G	—	uncertain significance
rs746168998	6:18,166,537	A/C	—	uncertain significance
rs187686404	6:18,171,150	C/T	intron variant	—
rs1306422029	6:18,171,595	T/C	—	uncertain significance
rs2534267760	6:18,171,615	T/A	—	uncertain significance
rs188911996	6:18,173,915	G/A	intron variant	—
rs754264817	6:18,197,354	G/A	—	uncertain significance
rs754993941	6:18,197,829	C/G	—	uncertain significance
rs771682921	6:18,197,875	C/T	—	uncertain significance
rs1787960151	6:18,200,670	G/A	—	uncertain significance
rs148006516	6:18,207,708	C/T	—	uncertain significance
rs777474479	6:18,208,393	G/C	—	uncertain significance
rs2535073141	6:18,215,302	A/G	—	uncertain significance
rs749742450	6:18,215,314	T/C	—	uncertain significance
rs200223055	6:18,215,335	C/T	—	uncertain significance
rs764138600	6:18,215,341	G/A	—	uncertain significance
rs751615354	6:18,215,351	C/G	—	uncertain significance
rs757510015	6:18,215,353	A/G	—	uncertain significance
rs74542809	6:18,217,956	G/C	—	benign
rs780847222	6:18,218,007	C/T	—	uncertain significance
rs778947998	6:18,222,191	G/A	—	uncertain significance
rs746150715	6:18,222,204	G/A	—	uncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.