Trait
SNPs associated with Alzheimer disease, age at onset
44 genetic variants across 16 genes have been associated with Alzheimer disease, age at onset in published research. Key genes include APOC1, HSD17B12, KDM1B.
Associated variants44 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs56131196 | APOC1 | GWAS association (p=3.0e-24) | Large GWAS |
| rs4420638 | APOC1 | GWAS association (p=2.0e-16) | Large GWAS |
| rs183826639 | — | GWAS association (p=1.0e-12) | Large GWAS |
| rs76930906 | LINC02268 | GWAS association (p=3.0e-11) | Large GWAS |
| rs61860854 | LOC105378318 | GWAS association (p=3.0e-11) | Large GWAS |
| rs118152978 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs188420713 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs75885813 | RBFOX1 | GWAS association (p=4.0e-10) | Large GWAS |
| rs147028191 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs183757472 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs118099348 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs117483990 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs115291397 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs139675748 | HSD17B12 | GWAS association (p=2.0e-09) | Large GWAS |
| rs147991290 | SYNJ1 | GWAS association (p=3.0e-09) | Large GWAS |
| rs115514216 | LINC02699 | GWAS association (p=3.0e-09) | Large GWAS |
| rs143638193 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs150511909 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs147525344 | — | GWAS association (p=5.0e-09) | Large GWAS |
| rs12041233 | — | GWAS association (p=6.0e-09) | Large GWAS |
| rs187293782 | LOC105369844 | GWAS association (p=7.0e-09) | Large GWAS |
| rs4557697 | — | GWAS association (p=8.0e-09) | Large GWAS |
| rs17639982 | — | GWAS association (p=8.0e-09) | Large GWAS |
| rs145049847 | SDR42E2 | GWAS association (p=8.0e-09) | Large GWAS |
| rs143083071 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs115809613 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs183600932 | PHF14 | GWAS association (p=1.0e-08) | Large GWAS |
| rs113118940 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs79781504 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs75009721 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs189421534 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs144288546 | TMEM132C | GWAS association (p=2.0e-08) | Large GWAS |
| rs211257 | LOC105376485 | GWAS association (p=2.0e-08) | Large GWAS |
| rs188911996 | KDM1B | GWAS association (p=2.0e-08) | Large GWAS |
| rs16887604 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs2970989 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs7609954 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs146650065 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs138090874 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs2962508 | LARS1 | GWAS association (p=4.0e-08) | Large GWAS |
| rs191975838 | LOC730100 | GWAS association (p=5.0e-08) | Large GWAS |
| rs1347297 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs6927354 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs190780914 | LOC105378392 | GWAS association (p=5.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.