LRFN2
leucine rich repeat and fibronectin type III domain containing 2
Summary
Predicted to be involved in modulation of chemical synaptic transmission and regulation of postsynapse organization. Predicted to be located in plasma membrane. Predicted to be active in several cellular components, including Schaffer collateral - CA1 synapse; cell surface; and postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2025]
Known Variants49 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs201632417 | 6:40,359,816 | G/A | — | uncertain significance |
| rs142012380 | 6:40,359,835 | C/A | — | likely benign |
| rs771949075 | 6:40,359,836 | G/C | — | uncertain significance |
| rs150683269 | 6:40,359,840 | C/T | — | uncertain significance |
| rs267601025 | 6:40,359,879 | C/T | — | uncertain significance |
| rs769620701 | 6:40,359,999 | C/G | — | uncertain significance |
| rs748767630 | 6:40,360,002 | C/T | — | uncertain significance |
| rs377192362 | 6:40,360,013 | G/A | — | uncertain significance |
| rs1281598144 | 6:40,360,090 | G/C | — | uncertain significance |
| rs201915132 | 6:40,360,110 | G/A | — | uncertain significance |
| rs776997956 | 6:40,360,112 | G/C | — | uncertain significance |
| rs767653363 | 6:40,360,130 | C/T | — | uncertain significance |
| rs554983231 | 6:40,360,142 | C/T | — | uncertain significance |
| rs574860936 | 6:40,360,152 | C/A | — | uncertain significance |
| rs2532514669 | 6:40,360,192 | G/C | — | uncertain significance |
| rs61745019 | 6:40,360,200 | C/A | — | uncertain significance |
| rs765288706 | 6:40,360,239 | G/A | — | uncertain significance |
| rs200804161 | 6:40,360,265 | G/A | — | likely benign |
| rs765272532 | 6:40,360,298 | G/A | — | uncertain significance |
| rs562066173 | 6:40,360,401 | C/T | — | uncertain significance |
| rs1485565179 | 6:40,360,458 | C/T | — | uncertain significance |
| rs376037708 | 6:40,360,522 | G/A | — | likely benign |
| rs1762542356 | 6:40,360,592 | T/C | — | uncertain significance |
| rs56084097 | 6:40,361,491 | C/A | intron variant | — |
| rs146724906 | 6:40,399,510 | C/T | — | uncertain significance |
| rs201054196 | 6:40,399,588 | G/A | — | uncertain significance |
| rs150417685 | 6:40,399,622 | C/G | — | uncertain significance |
| rs767471179 | 6:40,399,633 | C/T | — | uncertain significance |
| rs148386118 | 6:40,399,690 | C/T | — | uncertain significance |
| rs143308770 | 6:40,399,724 | C/T | — | uncertain significance |
| rs2532285128 | 6:40,399,772 | C/A | — | uncertain significance |
| rs201182634 | 6:40,399,877 | C/T | — | uncertain significance |
| rs376487545 | 6:40,399,994 | C/T | — | uncertain significance |
| rs1463506069 | 6:40,400,030 | A/G | — | uncertain significance |
| rs138583599 | 6:40,400,093 | G/A | — | uncertain significance |
| rs140980612 | 6:40,400,194 | C/T | — | uncertain significance |
| rs150204126 | 6:40,400,195 | G/A | — | uncertain significance |
| rs558213890 | 6:40,400,359 | G/A | — | uncertain significance |
| rs375159497 | 6:40,400,441 | C/T | — | uncertain significance |
| rs368148915 | 6:40,400,442 | G/A | — | likely benign |
| rs148439555 | 6:40,400,462 | C/T | — | uncertain significance |
| rs149939756 | 6:40,400,795 | C/T | — | uncertain significance |
| rs372128492 | 6:40,400,825 | C/T | — | uncertain significance |
| rs149178002 | 6:40,400,837 | C/G | — | uncertain significance |
| rs28385630 | 6:40,400,877 | G/A | splice region variant | — |
| rs148751765 | 6:40,427,310 | T/G | intron variant | — |
| rs9296335 | 6:40,440,500 | G/A | intron variant | — |
| rs9471365 | 6:40,503,394 | T/C | intron variant | — |
| rs2494938 | 6:40,536,128 | G/A | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.