NKX2-3
NK2 homeobox 3
Summary
This gene encodes a homeodomain-containing transcription factor. The encoded protein is a member of the NKX family of homeodomain transcription factors. Studies of similar proteins in mouse and rat have indicated a potential role in cellular differentiation.[provided by RefSeq, Mar 2010]
Known Variants29 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs10883369 | 10:101,291,367 | C/A | — | — |
| rs11190140 | 10:101,291,593 | T/C | upstream gene variant | — |
| rs11190141 | 10:101,292,390 | C/T | regulatory region variant | — |
| rs372618389 | 10:101,292,959 | A/G | — | uncertain significance |
| rs199963044 | 10:101,293,025 | T/C | — | uncertain significance |
| rs41290504 | 10:101,293,035 | C/A | synonymous variant | — |
| rs753335295 | 10:101,293,039 | G/A | — | uncertain significance |
| rs754498950 | 10:101,293,043 | G/A | — | uncertain significance |
| rs1317737522 | 10:101,293,088 | G/C | — | uncertain significance |
| rs370885897 | 10:101,293,141 | T/G | — | uncertain significance |
| rs2494260122 | 10:101,293,185 | C/G | — | uncertain significance |
| rs2494260142 | 10:101,293,195 | G/A | — | uncertain significance |
| rs745817982 | 10:101,293,208 | A/G | — | uncertain significance |
| rs780254468 | 10:101,293,219 | C/A | — | uncertain significance |
| rs774453161 | 10:101,293,234 | G/T | — | uncertain significance |
| rs2033953424 | 10:101,294,835 | C/T | — | uncertain significance |
| rs184601313 | 10:101,294,851 | G/A | — | likely benign |
| rs747305522 | 10:101,294,885 | A/G | — | uncertain significance |
| rs369954020 | 10:101,294,997 | G/A | — | uncertain significance |
| rs772952098 | 10:101,295,062 | G/A | — | uncertain significance |
| rs1324072957 | 10:101,295,086 | G/C | — | uncertain significance |
| rs1241882106 | 10:101,295,125 | G/A | — | uncertain significance |
| rs2494264220 | 10:101,295,170 | C/T | — | uncertain significance |
| rs1391888481 | 10:101,295,229 | A/T | — | likely benign |
| rs903996123 | 10:101,295,232 | A/T | — | likely benign |
| rs1361105137 | 10:101,295,245 | A/G | — | uncertain significance |
| rs1181122077 | 10:101,295,303 | C/T | — | uncertain significance |
| rs151053941 | 10:101,295,456 | T/G | missense variant | — |
| rs888208 | 10:101,295,863 | A/G | upstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.