PHACTR4
phosphatase and actin regulator 4
Summary
This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Known Variants41 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs67856516 | 1:28,697,135 | C/T | — | — |
| rs4908348 | 1:28,706,949 | T/G | intron variant | — |
| rs61783804 | 1:28,717,871 | T/C | intron variant | — |
| rs4615861 | 1:28,730,212 | C/A | intron variant | — |
| rs60781079 | 1:28,730,817 | G/C | — | — |
| rs67558364 | 1:28,745,642 | G/T | — | — |
| rs776213839 | 1:28,764,932 | G/A | — | uncertain significance |
| rs1407964167 | 1:28,785,621 | G/T | — | likely benign |
| rs755320061 | 1:28,785,667 | C/T | — | uncertain significance |
| rs2524956573 | 1:28,785,670 | A/C | — | uncertain significance |
| rs774648598 | 1:28,785,680 | A/G | — | uncertain significance |
| rs762730952 | 1:28,785,700 | G/T | — | uncertain significance |
| rs550399400 | 1:28,785,730 | A/G | — | uncertain significance |
| rs759224347 | 1:28,786,731 | C/T | — | uncertain significance |
| rs757878355 | 1:28,792,208 | C/T | — | uncertain significance |
| rs778120577 | 1:28,792,238 | A/G | — | uncertain significance |
| rs375917926 | 1:28,792,280 | C/T | — | uncertain significance |
| rs1407392913 | 1:28,792,977 | C/T | — | uncertain significance |
| rs375108461 | 1:28,793,054 | A/C | — | uncertain significance |
| rs1206603979 | 1:28,793,249 | C/T | — | uncertain significance |
| rs1659200147 | 1:28,793,256 | A/T | — | uncertain significance |
| rs2525030186 | 1:28,800,068 | G/A | — | uncertain significance |
| rs1659716616 | 1:28,800,090 | G/C | — | uncertain significance |
| rs145957277 | 1:28,800,110 | C/G | — | uncertain significance |
| rs200234997 | 1:28,800,111 | C/T | — | uncertain significance |
| rs543879394 | 1:28,800,119 | C/A | — | uncertain significance |
| rs2525030748 | 1:28,800,141 | T/C | — | uncertain significance |
| rs766215270 | 1:28,800,222 | C/T | — | uncertain significance |
| rs368189063 | 1:28,800,230 | A/G | — | likely benign |
| rs201971538 | 1:28,800,291 | A/G | — | uncertain significance |
| rs61785974 | 1:28,800,380 | C/A | missense variant | — |
| rs2525033264 | 1:28,800,394 | T/G | — | uncertain significance |
| rs200906297 | 1:28,800,615 | C/T | — | uncertain significance |
| rs2525034980 | 1:28,800,648 | T/C | — | uncertain significance |
| rs376686876 | 1:28,802,676 | G/C | — | likely benign |
| rs377530308 | 1:28,807,009 | G/T | — | uncertain significance |
| rs1476544280 | 1:28,807,088 | C/T | — | uncertain significance |
| rs2525068446 | 1:28,807,109 | C/G | — | uncertain significance |
| rs2525133630 | 1:28,818,238 | A/G | — | uncertain significance |
| rs1490537685 | 1:28,819,540 | A/C | — | uncertain significance |
| rs58953363 | 1:28,820,022 | C/G | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.