PRDM11
PR/SET domain 11
Summary
Predicted to enable DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including negative regulation of cell growth; positive regulation of fibroblast apoptotic process; and regulation of DNA-templated transcription. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants11 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs76158292 | 11:45,123,226 | G/A | — | — |
| rs1035312903 | 11:45,159,736 | G/A | — | — |
| rs10742746 | 11:45,198,688 | T/C | intron variant | — |
| rs17723470 | 11:45,227,567 | C/T | intron variant | — |
| rs12284404 | 11:45,228,686 | G/A | intron variant | — |
| rs2863166 | 11:45,229,091 | G/C | — | — |
| rs3758725 | 11:45,241,729 | C/G | intron variant | — |
| rs714215 | 11:45,246,869 | A/G | downstream gene variant | — |
| rs2863171 | 11:45,250,732 | A/C | downstream gene variant | — |
| rs149479122 | 11:45,253,304 | C/T | intron variant | — |
| rs4433560 | 11:45,253,866 | T/A | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.