SCAI
suppressor of cancer cell invasion
Summary
This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]
Known Variants36 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs775189186 | 9:127,715,157 | G/T | — | uncertain significance |
| rs200979758 | 9:127,715,169 | G/T | — | uncertain significance |
| rs28942070 | 9:127,730,689 | A/C | coding sequence variant | — |
| rs756508043 | 9:127,733,690 | T/C | — | uncertain significance |
| rs1016280095 | 9:127,733,732 | A/G | — | uncertain significance |
| rs202109345 | 9:127,733,958 | C/T | — | uncertain significance |
| rs200076178 | 9:127,733,988 | C/T | — | uncertain significance |
| rs765417164 | 9:127,734,094 | G/A | — | uncertain significance |
| rs2491130759 | 9:127,738,464 | T/C | — | uncertain significance |
| rs775009298 | 9:127,764,258 | C/T | — | uncertain significance |
| rs1203143896 | 9:127,764,309 | T/C | — | uncertain significance |
| rs2491191603 | 9:127,765,766 | C/G | — | uncertain significance |
| rs2491191720 | 9:127,765,807 | G/C | — | uncertain significance |
| rs558484642 | 9:127,777,960 | T/C | — | — |
| rs777075487 | 9:127,781,101 | T/C | — | uncertain significance |
| rs200657393 | 9:127,781,108 | G/C | — | uncertain significance |
| rs749607765 | 9:127,781,450 | C/T | — | uncertain significance |
| rs2491240913 | 9:127,783,039 | C/A | — | uncertain significance |
| rs763999121 | 9:127,790,740 | C/A | — | uncertain significance |
| rs759322366 | 9:127,792,018 | T/C | — | likely benign |
| rs71497076 | 9:127,794,467 | T/A | — | — |
| rs373100131 | 9:127,818,164 | T/C | — | uncertain significance |
| rs588818 | 9:127,821,554 | A/G | intron variant | — |
| rs142378207 | 9:127,825,168 | G/A | intron variant | — |
| rs637473 | 9:127,825,505 | T/C | intron variant | — |
| rs59842227 | 9:127,836,760 | C/A | — | — |
| rs72765265 | 9:127,838,223 | C/T | regulatory region variant | — |
| rs72765272 | 9:127,851,931 | A/C | intron variant | — |
| rs72765277 | 9:127,858,106 | A/C | intron variant | — |
| rs191242857 | 9:127,870,796 | G/A | intron variant | — |
| rs10819036 | 9:127,890,913 | T/C | intron variant | — |
| rs60042780 | 9:127,894,214 | G/A | regulatory region variant | — |
| rs55667828 | 9:127,897,940 | A/T | — | — |
| rs56118607 | 9:127,898,024 | G/A | intron variant | — |
| rs149411756 | 9:127,900,635 | A/G | intron variant | — |
| rs764533096 | 9:127,904,936 | T/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.