SCGB1A1
secretoglobin family 1A member 1
Summary
This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq, May 2010]
Known Variants10 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs190671103 | 11:62,184,928 | G/A | upstream gene variant | — |
| rs41364547 | 11:62,186,530 | G/G | — | uncertain significance |
| rs3741240 | 11:62,186,542 | G/A | downstream gene variant | association |
| rs4963506 | 11:62,187,666 | G/A | regulatory region variant | — |
| rs150406817 | 11:62,189,693 | C/T | — | uncertain significance |
| rs550040069 | 11:62,189,711 | C/T | — | uncertain significance |
| rs202225101 | 11:62,189,712 | G/A | — | likely benign |
| rs41465250 | 11:62,189,736 | C/T | — | benign |
| rs760802019 | 11:62,189,879 | T/C | — | likely benign |
| rs1937842519 | 11:62,190,553 | T/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.