SH3PXD2A

SH3 and PX domains 2A

Summary

Predicted to enable superoxide-generating NADPH oxidase activator activity. Involved in osteoclast fusion and superoxide metabolic process. Located in cytosol and podosome. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants110 total

rsidPosition (GRCh37)AllelesClassClinVar
rs95132984610:105,361,595T/G—uncertain significance
rs75538614810:105,361,636G/C—uncertain significance
rs56168108210:105,361,743C/T—uncertain significance
rs37584344310:105,361,770T/G—uncertain significance
rs13977395510:105,361,775T/C—uncertain significance
rs37555478710:105,361,812C/A—uncertain significance
rs491803110:105,361,816T/Gsynonymous variant—
rs124857644710:105,361,832G/A—uncertain significance
rs378136510:105,361,871C/T—benign
rs55381840910:105,361,883C/T—uncertain significance
rs77886731910:105,361,898G/A—uncertain significance
rs75259654910:105,361,899C/T—uncertain significance
rs14505934110:105,361,905C/T—uncertain significance
rs36983629110:105,361,910C/T—uncertain significance
rs7906193210:105,361,911G/A—likely benign
rs7592259410:105,361,941C/T—benign
rs14620369810:105,361,982C/T—uncertain significance
rs76399740510:105,362,018G/A—uncertain significance
rs120370194410:105,362,033G/A—uncertain significance
rs37380591410:105,362,048G/A—uncertain significance
rs37738758610:105,362,051A/G—uncertain significance
rs254085522210:105,362,071C/T—uncertain significance
rs13823937910:105,362,112C/T—uncertain significance
rs11514930810:105,362,137C/T—benign
rs77384469610:105,362,142C/T—uncertain significance
rs20184055310:105,362,152C/G—uncertain significance
rs77830493410:105,362,187C/T—uncertain significance
rs37125561810:105,362,217C/T—uncertain significance
rs254085612110:105,362,246T/C—uncertain significance
rs75800172510:105,362,292C/T—benign
rs77572287210:105,362,349C/T—uncertain significance
rs76311508710:105,362,369A/G—uncertain significance
rs203623573810:105,362,384C/G—uncertain significance
rs14515011610:105,362,550C/T—uncertain significance
rs37044527510:105,362,600A/T—uncertain significance
rs54995785010:105,362,606C/A—uncertain significance
rs74840489910:105,362,609C/T—uncertain significance
rs77029779410:105,362,637G/A—uncertain significance
rs203624061810:105,362,671C/G—uncertain significance
rs37164042710:105,362,684C/T—uncertain significance
rs14039141310:105,362,705C/T—uncertain significance
rs75819295510:105,362,711G/A—uncertain significance
rs78156074510:105,362,787C/T—uncertain significance
rs76931084110:105,362,814G/A—uncertain significance
rs14280648610:105,362,826C/T—uncertain significance
rs37650493510:105,363,057C/T—likely benign
rs75201973310:105,363,158C/T—uncertain significance
rs15089615610:105,363,169G/A—benign
rs14010831510:105,363,171G/A—uncertain significance
rs77693685610:105,363,197G/A—uncertain significance
rs76300822610:105,363,216C/G—uncertain significance
rs37710044010:105,363,249C/T—uncertain significance
rs77709285310:105,363,329C/T—uncertain significance
rs74910300610:105,363,462G/A—uncertain significance
rs254086140110:105,363,474A/G—uncertain significance
rs37422135610:105,365,574C/T—uncertain significance
rs146749410010:105,365,580C/T—uncertain significance
rs75534869110:105,371,381G/A—uncertain significance
rs91996647010:105,372,654C/A—uncertain significance
rs77113650310:105,372,688C/T—likely benign
rs75964414710:105,372,783G/A—uncertain significance
rs116245532210:105,372,799C/T—uncertain significance
rs135701870410:105,372,827G/C—uncertain significance
rs254088731110:105,372,890G/T—uncertain significance
rs98451426210:105,372,924G/A—uncertain significance
rs203645447010:105,372,932C/G—uncertain significance
rs1224319610:105,375,357G/Aregulatory region variant—
rs254089705710:105,376,957A/G—uncertain significance
rs14403318710:105,386,860G/A—uncertain significance
rs97312789410:105,386,885G/A—uncertain significance
rs7833971210:105,387,528C/Tintron variant—
rs1088389010:105,390,021G/T——
rs7333335310:105,415,859G/Aintron variant—
rs77243099210:105,420,834A/G—uncertain significance
rs74999497210:105,420,855C/T—uncertain significance
rs126056777710:105,420,860G/T—likely benign
rs77862680610:105,420,864C/T—likely benign
rs54632394210:105,443,432C/A——
rs5769467010:105,447,782A/Gintron variant—
rs286399410:105,454,043T/Gintron variant—
rs791788010:105,471,768A/T——
rs13997112410:105,484,109C/T—uncertain significance
rs254109507510:105,495,501C/T—uncertain significance
rs128642247910:105,495,521T/C—uncertain significance
rs14032469910:105,495,531C/T—uncertain significance
rs77579331810:105,495,536C/T—uncertain significance
rs1119179410:105,516,521C/Tregulatory region variant—
rs107681310:105,517,652A/Gregulatory region variant—
rs792339610:105,518,688T/Cintron variant—
rs1074884910:105,530,086C/Tintron variant—
rs3459427110:105,548,084C/Tintron variant—
rs7862361410:105,561,032A/C—benign
rs14236366610:105,561,046G/T—uncertain significance
rs249286628910:105,561,056T/C—uncertain significance
rs56684512210:105,561,107T/C—uncertain significance
rs74324010:105,579,594G/C——
rs19309775310:105,585,753C/Tintron variant—
rs13962015110:105,593,428G/Aintron variant—
rs491805810:105,596,641G/A——
rs1119182210:105,599,770T/Gregulatory region variant—

Showing 100 of 110 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.