SRPK2
SRSF protein kinase 2
Summary
Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in several processes, including R-loop processing; peptidyl-serine phosphorylation; and regulation of viral genome replication. Located in chromatin; cytosol; and nuclear lumen. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants49 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1142 | 7:104,756,326 | C/G | — | — |
| rs6968355 | 7:104,758,250 | T/C | downstream gene variant | — |
| rs2536559432 | 7:104,758,340 | G/A | — | uncertain significance |
| rs755562838 | 7:104,766,704 | T/G | — | uncertain significance |
| rs375304054 | 7:104,766,715 | C/T | — | uncertain significance |
| rs1050419 | 7:104,766,732 | T/C | — | likely benign |
| rs371115678 | 7:104,773,244 | C/T | — | likely benign |
| rs758052569 | 7:104,773,247 | C/T | — | likely benign |
| rs1432441754 | 7:104,773,248 | G/A | — | uncertain significance |
| rs56172322 | 7:104,773,262 | C/T | — | likely benign |
| rs373228452 | 7:104,773,507 | G/A | — | uncertain significance |
| rs1481702844 | 7:104,782,460 | G/A | — | uncertain significance |
| rs56112661 | 7:104,782,508 | G/A | — | uncertain significance |
| rs766607613 | 7:104,782,608 | A/G | — | uncertain significance |
| rs56003957 | 7:104,782,648 | T/C | — | benign |
| rs749128807 | 7:104,782,655 | T/C | — | uncertain significance |
| rs55743527 | 7:104,782,689 | T/G | — | uncertain significance |
| rs756424370 | 7:104,782,747 | T/G | — | likely benign |
| rs764040097 | 7:104,782,750 | T/A | — | uncertain significance |
| rs536793006 | 7:104,782,762 | T/A | — | uncertain significance |
| rs143341338 | 7:104,782,848 | T/C | — | uncertain significance |
| rs556687655 | 7:104,782,853 | G/T | — | uncertain significance |
| rs140151965 | 7:104,782,873 | A/G | — | benign |
| rs2240464 | 7:104,782,888 | A/T | — | benign |
| rs1366668983 | 7:104,782,922 | T/C | — | uncertain significance |
| rs1584935180 | 7:104,783,590 | A/C | — | uncertain significance |
| rs1804050251 | 7:104,783,629 | G/A | — | likely benign |
| rs377259714 | 7:104,783,663 | T/C | — | uncertain significance |
| rs149027278 | 7:104,785,735 | T/G | — | uncertain significance |
| rs770484759 | 7:104,801,044 | G/A | — | likely benign |
| rs771518461 | 7:104,801,064 | G/C | — | likely benign |
| rs56666353 | 7:104,808,539 | C/T | — | benign |
| rs147076434 | 7:104,808,540 | C/T | — | uncertain significance |
| rs1332902916 | 7:104,809,670 | C/T | — | uncertain significance |
| rs1401523336 | 7:104,809,671 | G/A | — | uncertain significance |
| rs10607748 | 7:104,817,056 | G/T | — | — |
| rs60944281 | 7:104,822,351 | C/A | — | — |
| rs1248107190 | 7:104,844,085 | G/C | — | uncertain significance |
| rs1380771554 | 7:104,844,163 | A/T | — | likely benign |
| rs56318802 | 7:104,844,229 | C/T | — | benign |
| rs10281422 | 7:104,844,519 | G/C | — | — |
| rs73186025 | 7:104,878,705 | C/T | — | — |
| rs4580973 | 7:104,903,659 | A/C | — | — |
| rs73186041 | 7:104,916,716 | G/A | — | — |
| rs7789569 | 7:104,927,586 | T/C | intron variant | — |
| rs6466055 | 7:104,929,064 | A/C | intron variant | — |
| rs10429247 | 7:104,937,699 | A/G | upstream gene variant | — |
| rs146307731 | 7:105,029,121 | C/T | — | likely benign |
| rs190731348 | 7:105,029,723 | G/A | — | benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.