SWAP70
switching B cell complex subunit SWAP70
Summary
Enables cadherin binding activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to act upstream of or within isotype switching. Located in actin cytoskeleton; cytoplasm; and plasma membrane. Is active in postsynapse. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants36 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2494311372 | 11:9,685,737 | T/C | — | uncertain significance |
| rs371975558 | 11:9,685,769 | G/A | — | uncertain significance |
| rs532270112 | 11:9,707,379 | C/T | — | — |
| rs778387589 | 11:9,715,735 | G/T | — | uncertain significance |
| rs1357916873 | 11:9,715,741 | G/A | — | uncertain significance |
| rs752785142 | 11:9,735,152 | A/T | — | uncertain significance |
| rs2494398539 | 11:9,746,314 | C/T | — | likely benign |
| rs1400451298 | 11:9,746,359 | G/A | — | uncertain significance |
| rs560808312 | 11:9,746,367 | C/T | — | uncertain significance |
| rs756309764 | 11:9,749,627 | C/T | — | uncertain significance |
| rs1166461418 | 11:9,749,669 | A/T | — | uncertain significance |
| rs2494405027 | 11:9,749,739 | G/A | — | uncertain significance |
| rs2494406623 | 11:9,750,986 | G/C | — | uncertain significance |
| rs9943599 | 11:9,752,741 | C/G | — | — |
| rs360158 | 11:9,753,601 | G/T | — | — |
| rs373881926 | 11:9,754,168 | C/G | — | uncertain significance |
| rs769550588 | 11:9,754,200 | G/C | — | uncertain significance |
| rs1187966951 | 11:9,754,202 | A/C | — | uncertain significance |
| rs1055207838 | 11:9,754,249 | G/T | — | uncertain significance |
| rs777556056 | 11:9,759,801 | G/T | — | uncertain significance |
| rs2494418767 | 11:9,759,819 | A/C | — | uncertain significance |
| rs375914980 | 11:9,759,829 | C/G | — | uncertain significance |
| rs369952707 | 11:9,761,751 | G/C | — | uncertain significance |
| rs199611519 | 11:9,761,797 | C/T | — | uncertain significance |
| rs2494420974 | 11:9,761,825 | T/C | — | uncertain significance |
| rs10840298 | 11:9,764,832 | C/T | — | — |
| rs4910498 | 11:9,765,503 | A/T | intron variant | — |
| rs378825 | 11:9,766,932 | A/G | regulatory region variant | — |
| rs491205 | 11:9,767,559 | G/A | regulatory region variant | — |
| rs147789282 | 11:9,769,488 | C/T | — | uncertain significance |
| rs765284993 | 11:9,769,547 | A/G | — | uncertain significance |
| rs1851534171 | 11:9,769,556 | C/G | — | likely benign |
| rs766662979 | 11:9,769,577 | C/G | — | uncertain significance |
| rs472109 | 11:9,770,318 | G/T | — | — |
| rs1169240440 | 11:9,770,641 | A/G | — | uncertain significance |
| rs570665128 | 11:9,770,821 | G/A | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.