TMEM50A
transmembrane protein 50A
Summary
This gene is located in the RH gene locus, between the RHD and RHCE genes. The function of its protein product is unknown; however, its sequence has potential transmembrane domains suggesting that it may be an integral membrane protein. Its position between the RH genes suggests that polymorphisms in this gene may be tightly linked to RH haplotypes and may contribute to selective pressure for or against certain RH haplotypes. [provided by RefSeq, Jul 2008]
Known Variants11 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs596608 | 1:25,663,071 | C/G | upstream gene variant | — |
| rs75558785 | 1:25,666,747 | A/T | upstream gene variant | — |
| rs147456847 | 1:25,667,024 | G/T | — | uncertain significance |
| rs9645452 | 1:25,668,326 | C/T | upstream gene variant | — |
| rs372524637 | 1:25,668,378 | T/G | — | — |
| rs3091242 | 1:25,674,785 | C/T | upstream gene variant | — |
| rs114247628 | 1:25,675,530 | G/A | upstream gene variant | — |
| rs3091240 | 1:25,676,935 | G/T | upstream gene variant | — |
| rs774445401 | 1:25,679,379 | G/A | — | uncertain significance |
| rs146519311 | 1:25,679,438 | A/G | — | uncertain significance |
| rs138543922 | 1:25,688,042 | C/T | regulatory region variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.