TP53INP1
tumor protein p53 inducible nuclear protein 1
Summary
Predicted to enable antioxidant activity. Involved in autophagic cell death; positive regulation of DNA-templated transcription; and positive regulation of autophagy. Located in autophagosome; cytosol; and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants30 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs771192696 | 8:95,942,717 | T/C | — | uncertain significance |
| rs777588834 | 8:95,942,723 | C/T | — | uncertain significance |
| rs774428478 | 8:95,942,760 | T/G | — | uncertain significance |
| rs866529450 | 8:95,942,798 | C/T | — | uncertain significance |
| rs150114023 | 8:95,942,799 | G/A | — | uncertain significance |
| rs185282859 | 8:95,942,801 | C/G | — | uncertain significance |
| rs138400077 | 8:95,942,806 | G/C | — | uncertain significance |
| rs1476052610 | 8:95,942,822 | G/A | — | uncertain significance |
| rs772155217 | 8:95,942,861 | C/T | — | uncertain significance |
| rs201253664 | 8:95,942,927 | T/C | — | uncertain significance |
| rs62523081 | 8:95,946,160 | G/A | intron variant | — |
| rs113910919 | 8:95,949,666 | C/G | intron variant | — |
| rs767105335 | 8:95,950,081 | C/T | — | — |
| rs1423249742 | 8:95,952,166 | T/C | — | uncertain significance |
| rs1178902999 | 8:95,952,247 | G/A | — | uncertain significance |
| rs200402440 | 8:95,952,257 | G/C | — | uncertain significance |
| rs746702622 | 8:95,952,266 | T/C | — | uncertain significance |
| rs753959036 | 8:95,952,337 | C/A | — | uncertain significance |
| rs779919334 | 8:95,952,352 | G/A | — | uncertain significance |
| rs372079851 | 8:95,952,386 | G/A | — | uncertain significance |
| rs199746482 | 8:95,953,099 | T/C | — | likely benign |
| rs780591115 | 8:95,953,116 | G/C | — | uncertain significance |
| rs4735333 | 8:95,955,074 | G/C | — | — |
| rs896854 | 8:95,960,511 | T/G | — | — |
| rs1320164 | 8:95,960,767 | G/T | — | — |
| rs896853 | 8:95,960,855 | G/T | — | — |
| rs896852 | 8:95,960,886 | G/C | — | — |
| rs2879813 | 8:95,960,947 | A/G | regulatory region variant | — |
| rs10108430 | 8:95,961,794 | C/G | — | — |
| rs7003387 | 8:95,961,979 | C/G | regulatory region variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.