TRIM59
tripartite motif containing 59
Summary
Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within negative regulation of canonical NF-kappaB signal transduction. Predicted to be located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants36 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs6785881 | 3:160,153,989 | C/T | downstream gene variant | — |
| rs1047210 | 3:160,154,258 | A/C | downstream gene variant | — |
| rs61758109 | 3:160,155,764 | T/C | — | likely benign |
| rs895274943 | 3:160,155,783 | C/T | — | likely benign |
| rs764304665 | 3:160,155,797 | A/G | — | uncertain significance |
| rs1719062835 | 3:160,155,801 | A/T | — | uncertain significance |
| rs2473788000 | 3:160,155,815 | A/G | — | uncertain significance |
| rs774589319 | 3:160,155,842 | T/C | — | uncertain significance |
| rs961819527 | 3:160,155,888 | T/C | — | likely benign |
| rs1484437579 | 3:160,155,957 | A/G | — | uncertain significance |
| rs751331451 | 3:160,155,965 | G/A | — | uncertain significance |
| rs978390841 | 3:160,155,989 | T/C | — | uncertain significance |
| rs746236973 | 3:160,156,042 | T/A | — | uncertain significance |
| rs201846537 | 3:160,156,046 | G/A | — | uncertain significance |
| rs140620378 | 3:160,156,143 | T/C | — | uncertain significance |
| rs1315572689 | 3:160,156,192 | A/T | — | uncertain significance |
| rs1358347667 | 3:160,156,319 | T/C | — | uncertain significance |
| rs2108514640 | 3:160,156,329 | T/A | — | uncertain significance |
| rs779124243 | 3:160,156,358 | G/T | — | uncertain significance |
| rs2473013314 | 3:160,156,407 | A/G | — | uncertain significance |
| rs144731211 | 3:160,156,431 | C/A | — | uncertain significance |
| rs375673052 | 3:160,156,451 | G/A | — | uncertain significance |
| rs567703469 | 3:160,156,458 | A/C | — | uncertain significance |
| rs754455288 | 3:160,156,490 | G/T | — | uncertain significance |
| rs371304886 | 3:160,156,494 | G/A | — | uncertain significance |
| rs148124731 | 3:160,156,502 | C/A | — | uncertain significance |
| rs758933583 | 3:160,156,567 | T/G | — | uncertain significance |
| rs202041217 | 3:160,156,568 | T/G | — | uncertain significance |
| rs141819524 | 3:160,156,647 | A/C | — | uncertain significance |
| rs771541438 | 3:160,156,691 | A/G | — | uncertain significance |
| rs763814578 | 3:160,156,707 | C/T | — | uncertain significance |
| rs376798956 | 3:160,156,794 | T/C | — | uncertain significance |
| rs139273294 | 3:160,156,820 | C/T | missense variant | — |
| rs990082989 | 3:160,156,910 | C/T | — | uncertain significance |
| rs149941048 | 3:160,156,943 | C/T | — | uncertain significance |
| rs17826221 | 3:160,160,452 | G/C | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.