rs1016140
This is a coding sequence variant variant in the CD58 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
systemic lupus erythematosus
Wang YF et al. “Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups.” Nature Communications 12(1):772 (2021)
Allele T
OR 0.87
p 3.0e-10
N 12,653
Large GWAS
East Asian
About CD58
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
View all CD58 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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