CD58
CD58 molecule
Summary
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
Known Variants21 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs376792396 | 1:117,057,443 | A/C | — | uncertain significance |
| rs10802190 | 1:117,061,384 | A/T | intron variant | — |
| rs2526148843 | 1:117,061,860 | T/C | — | uncertain significance |
| rs141064359 | 1:117,064,554 | G/A | — | likely benign |
| rs370263320 | 1:117,064,592 | G/C | — | likely benign |
| rs10802191 | 1:117,065,083 | T/G | — | — |
| rs1414275 | 1:117,066,907 | A/G | intron variant | — |
| rs11588376 | 1:117,072,524 | T/C | downstream gene variant | — |
| rs1016140 | 1:117,076,547 | G/T | coding sequence variant | — |
| rs758492590 | 1:117,078,589 | C/T | — | uncertain significance |
| rs1339807228 | 1:117,078,599 | T/C | — | likely benign |
| rs2525018997 | 1:117,078,728 | T/C | — | uncertain significance |
| rs35768283 | 1:117,078,729 | A/G | synonymous variant | — |
| rs376614019 | 1:117,086,969 | T/C | — | uncertain significance |
| rs1266661778 | 1:117,086,977 | G/A | — | uncertain significance |
| rs762708999 | 1:117,087,196 | T/C | — | uncertain significance |
| rs12044852 | 1:117,087,779 | C/A | regulatory region variant | — |
| rs10754324 | 1:117,093,035 | T/G | — | — |
| rs1335532 | 1:117,100,957 | A/G | regulatory region variant | benign |
| rs1414273 | 1:117,102,649 | C/G | coding sequence variant | — |
| rs2300747 | 1:117,104,215 | A/G | upstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.