rs10738607
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
low density lipoprotein cholesterol measurement
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.02
p 3.0e-22
N 578,857
Major Consortium StudyLarge GWAS
multi-ancestry
coronary artery disease
Wakil SM et al. “A genome-wide association study reveals susceptibility loci for myocardial infarction/coronary artery disease in Saudi Arabs.” Atherosclerosis 245:62-70 (2016)
Allele G
OR 1.28
p 2.0e-13
N 4,431
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)
myocardial infarction
Wakil SM et al. “A genome-wide association study reveals susceptibility loci for myocardial infarction/coronary artery disease in Saudi Arabs.” Atherosclerosis 245:62-70 (2016)
Allele G
OR 1.27
p 7.0e-13
N 4,431
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)
total cholesterol measurement
Klarin D et al. “Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.” Nature Genetics 50(11):1514-1523 (2018)
Allele A
OR 0.01
p 2.0e-9
N 297,626
Major Consortium StudyLarge GWAS
multi-ancestry
asthma, endometriosis
Adewuyi EO et al. “Genetic overlap analysis of endometriosis and asthma identifies shared loci implicating sex hormones and thyroid signalling pathways.” Human Reproduction (oxford, England) 37(2):366-383 (2022)
Allele A
OR —
β 0.052
p 2.0e-8
N 519,828
Large GWAS
East Asian, European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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