rs10745332
This variant is located in the CAPZA1 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
hypertension
Lu X et al. “Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.” Human Molecular Genetics 24(3):865-74 (2015)
Allele A
OR —
p 3.0e-9
N 9,469
Large GWAS
East Asian
systolic blood pressure
Lu X et al. “Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.” Human Molecular Genetics 24(3):865-74 (2015)
Allele A
OR 0.96
p 3.0e-9
N 11,816
Large GWAS
East Asian
About CAPZA1
CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. [provided by RefSeq, Jul 2008]
View all CAPZA1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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