rs10882398

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

systolic blood pressure

Allele A
OR 0.02
p 9.0e-23
N 394,642
Large GWAS
European

preeclampsia, hypertension, pregnancy-induced

Allele A
OR 1.11
p 2.0e-13
N 130,207
Large GWAS
European

aortic measurement

Benjamins JW et al. Genomic insights in ascending aortic size and distensibility. Ebiomedicine 75:103783 (2022)
Allele T
OR 0.04
p 3.0e-10
N 35,110
Large GWAS

preeclampsia

Honigberg MC et al. Polygenic prediction of preeclampsia and gestational hypertension. Nature Medicine 29(6):1540-1549 (2023)
Allele A
OR 5.92
p 3.0e-9
N 455,887
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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