rs10935478

GWAS Catalog Trait Associations (7)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

monocyte count

Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele T
OR 0.02
p 3.0e-20
N 444,975
Large GWAS
multi-ancestry

carbonic anhydrase 6 measurement

Allele T
OR 0.04
p 1.0e-16
N 47,745
Large GWAS
European

phospholipids in very large HDL measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 1.0e-16
N 136,016
Large GWAS
multi-ancestry

high density lipoprotein cholesterol measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 2.0e-16
N 136,016
Large GWAS
multi-ancestry

total lipids in very large HDL measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 7.0e-16
N 136,016
Large GWAS
multi-ancestry

phospholipids in medium LDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.01
p 6.0e-12
N 450,015
Large GWAS
multi-ancestry

cholesterol to total lipids in small LDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.01
p 7.0e-11
N 450,015
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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