rs10947428

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GWAS Catalog Trait Associations (7)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

platelet-to-lymphocyte ratio

Kachuri L et al. “Genetic determinants of blood-cell traits influence susceptibility to childhood acute lymphoblastic leukemia.” American Journal of Human Genetics 108(10):1823-1835 (2021)
Allele T
OR —
p 4.0e-35
N 234,552
Large GWAS
European

celiac disease

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele C
OR 0.37
p 7.0e-29
N 394,626
Large GWAS
European

insomnia

Watanabe K et al. “Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.” Nature Genetics 54(8):1125-1132 (2022)
Allele T
OR 0.01
p 2.0e-24
N 2,365,010
Meta-analysisLarge GWAS
European

allergic disease

Ferreira MA et al. “Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.” Nature Genetics 49(12):1752-1757 (2017)
Allele C
OR 1.05
p 4.0e-13
N 360,838
Large GWAS
European

osteoarthritis, knee

Hollis B et al. “Lifetime risk and genetic predisposition to post-traumatic OA of the knee in the UK Biobank.” Osteoarthritis and Cartilage 31(10):1377-1387 (2023)
Allele C
OR 1.04
p 5.0e-10
N 354,561
Major Consortium StudyLarge GWAS
European

insomnia measurement

Jansen PR et al. “Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.” Nature Genetics 51(3):394-403 (2019)
Allele C
OR 1.07
p 7.0e-15
N 1,331,010
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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