rs11066001
This is a upstream gene variant variant in the BRAP gene.
▶GWAS Catalog Trait Associations (12)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (12)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Red cell distribution width
Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)
Allele C
OR 0.10
p 5.0e-48
N 153,950
Large GWAS
East Asian
high density lipoprotein cholesterol measurement
Lee SB et al. “Dyslipidaemia-Genotype Interactions with Nutrient Intake and Cerebro-Cardiovascular Disease.” Biomedicines 10(7) (2022)
Allele C
OR 1.44
p 4.0e-46
N 58,701
Large GWAS
East Asian
mean corpuscular hemoglobin concentration
Chen MH et al. “Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.” Cell 182(5):1198-1213.e14 (2020)
Allele T
OR 0.08
p 1.0e-38
N 126,151
Large GWAS
East Asian
serum creatinine amount
Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)
Allele C
OR 0.05
p 5.0e-33
N 153,950
Large GWAS
East Asian
Flushing
Inoue Y et al. “Search for genetic loci involved in the constitution and skin type of a Japanese women using a genome-wide association study.” Experimental Dermatology 30(12):1787-1793 (2021)
Allele C
OR 0.40
p 4.0e-25
N 1,108
Large GWAS
East Asian
bilirubin measurement
Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)
Allele C
OR 0.05
p 9.0e-17
N 153,950
Large GWAS
East Asian
carbohydrate intake measurement
Nakamura Y et al. “A genome-wide association study on adherence to low-carbohydrate diets in Japanese.” European Journal of Clinical Nutrition 76(8):1103-1110 (2022)
Allele C
OR —
p 1.0e-14
N 14,076
Large GWAS
East Asian
BMI-adjusted waist-hip ratio
Cho HW et al. “A Genome-Wide Association Study of Novel Genetic Variants Associated With Anthropometric Traits in Koreans.” Frontiers in Genetics 12:669215 (2021)
Allele C
OR 0.00
p 3.0e-14
N 5,472
Large GWAS
East Asian
forced expiratory volume, body mass index
Zhu Z et al. “A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic aetiology with obesity.” The European Respiratory Journal 58(4) (2021)
Allele T
OR —
p 2.0e-11
N 100,285
Large GWAS
multi-ancestry
low density lipoprotein cholesterol measurement
Lee SB et al. “Dyslipidaemia-Genotype Interactions with Nutrient Intake and Cerebro-Cardiovascular Disease.” Biomedicines 10(7) (2022)
Allele C
OR 1.73
p 2.0e-11
N 58,701
Large GWAS
East Asian
About BRAP
The protein encoded by this gene was identified by its ability to bind to the nuclear localization signal of BRCA1 and other proteins. It is a cytoplasmic protein which may regulate nuclear targeting by retaining proteins with a nuclear localization signal in the cytoplasm. [provided by RefSeq, Jul 2008]
View all BRAP variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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