rs11741861

This is a intron variant variant in the ZNF300 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Crohn's disease

Liu JZ et al. “Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.” Nature Genetics 47(9):979-986 (2015)

Allele G

OR 1.33

p 6.0e-44

N 20,883

Large GWAS

multi-ancestry

inflammatory bowel disease

Jostins L et al. “Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.” Nature 491(7422):119-24 (2012)

Allele G

OR 1.25

p 3.0e-37

N 34,366

Large GWAS

European

About ZNF300

The protein encoded by this gene is a C2H2-type zinc finger DNA binding protein and likely transcriptional regulator. The function of this protein is not yet known. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]

View all ZNF300 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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