rs125124

This variant is located in the LINC-PINT gene.

GWAS Catalog Trait Associations (7)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

IGF-1 measurement

Allele G
OR 0.05
p 1.0e-131
N 394,642
Large GWAS
European

serum albumin amount

Allele C
OR 0.02
p 1.0e-35
N 928,679
Large GWAS
multi-ancestry
Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele C
OR 0.02
p 4.0e-16
N 435,807
Large GWAS
multi-ancestry

basal cell carcinoma

Allele G
OR 0.91
p 5.0e-35
N 812,765
Meta-analysisLarge GWAS
multi-ancestry
Liyanage UE et al. Combined analysis of keratinocyte cancers identifies novel genome-wide loci. Human Molecular Genetics 28(18):3148-3160 (2019)
Allele G
OR 1.10
p 1.0e-24
N 651,138
Large GWAS
European

cholesterol to total lipids in very large HDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.02
p 5.0e-20
N 450,015
Large GWAS
multi-ancestry

total blood protein measurement

Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele G
OR 0.02
p 5.0e-17
N 448,242
Large GWAS
multi-ancestry

gout

Major TJ et al. A genome-wide association analysis reveals new pathogenic pathways in gout. Nature Genetics 56(11):2392-2406 (2024)
Allele C
OR 1.05
p 9.0e-14
N 1,011,521
Large GWAS
European

urate measurement

Major TJ et al. A genome-wide association analysis reveals new pathogenic pathways in gout. Nature Genetics 56(11):2392-2406 (2024)
Allele C
OR 0.01
p 1.0e-8
N 630,117
Large GWAS
European
Cho C et al. Large-scale cross-ancestry genome-wide meta-analysis of serum urate. Nature Communications 15(1):3441 (2024)
Allele C
OR 0.01
p 4.0e-8
N 1,029,323
Meta-analysisLarge GWAS
multi-ancestry

About LINC-PINT

Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all LINC-PINT variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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