rs1275922

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

aging

Rosoff DB et al. “Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging.” Nature Aging 3(8):1020-1035 (2023)

Allele A

OR 0.01

p 3.0e-9

N 1,559,001

Large GWAS

European

parental longevity

Timmers PR et al. “Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances.” Elife 8 (2019)

Allele G

OR 0.26

p 6.0e-9

N 500,193

Large GWAS

European

healthspan, parental longevity, life span determination trait

Timmers PRHJ et al. “Multivariate genomic scan implicates novel loci and haem metabolism in human ageing.” Nature Communications 11(1):3570 (2020)

Allele G

OR —

p 2.0e-8

N 837,415

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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