Trait
SNPs associated with Parental Longevity
64 genetic variants across 29 genes have been associated with Parental Longevity in published research. Key genes include APOE, ATXN2, BEND3.
Associated variants64 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs429358 | APOE | GWAS association (p=3.0e-83) | Meta-analysis |
| rs8042849 | — | GWAS association (p=2.0e-26) | Meta-analysis |
| rs55730499 | LPA | GWAS association (p=2.0e-18) | Meta-analysis |
| rs10198124 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs34831921 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs10455872 | LPA | GWAS association (p=9.0e-25) | Major Consortium Study |
| rs72738736 | IREB2 | GWAS association (p=1.0e-23) | Major Consortium Study |
| rs186696265 | — | GWAS association (p=8.0e-18) | Major Consortium Study |
| rs1333042 | CDKN2B-AS1 | GWAS association (p=7.0e-15) | Major Consortium Study |
| rs7137828 | ATXN2 | GWAS association (p=3.0e-14) | Major Consortium Study |
| rs11065979 | — | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs9295128 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs4426183 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs1510224 | LPAL2 | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs11513729 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs28383322 | — | GWAS association (p=5.0e-11) | Major Consortium Study |
| rs17630235 | — | GWAS association (p=8.0e-11) | Major Consortium Study |
| rs11066309 | — | GWAS association (p=1.0e-10) | Major Consortium Study |
| rs17696736 | NAA25 | GWAS association (p=1.0e-10) | Major Consortium Study |
| rs6108784 | — | GWAS association (p=1.0e-10) | Major Consortium Study |
| rs3130507 | PSORS1C3 | GWAS association (p=2.0e-10) | Major Consortium Study |
| rs7844965 | — | GWAS association (p=6.0e-10) | Major Consortium Study |
| rs17514846 | FURIN | GWAS association (p=7.0e-10) | Major Consortium Study |
| rs143843429 | — | GWAS association (p=4.0e-09) | Major Consortium Study |
| rs1265564 | CUX2 | GWAS association (p=6.0e-09) | Major Consortium Study |
| rs61905747 | ZW10 | GWAS association (p=6.0e-09) | Major Consortium Study |
| rs12461964 | — | GWAS association (p=8.0e-09) | Major Consortium Study |
| rs3131621 | — | GWAS association (p=9.0e-09) | Major Consortium Study |
| rs74444983 | EXOC3L2 | GWAS association (p=9.0e-09) | Major Consortium Study |
| rs74011415 | SEMA6D | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs28926173 | MC2R | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs61978928 | PROX2 | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs2273500 | CHRNA4 | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs139137459 | USP2-AS1 | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs61949650 | — | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs13262617 | — | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs9456508 | — | GWAS association (p=4.0e-08) | Major Consortium Study |
| rs3184504 | SH2B3 | GWAS association (p=4.0e-08) | Major Consortium Study |
| rs1627804 | BEND3 | GWAS association (p=4.0e-08) | Major Consortium Study |
| rs146254978 | TNNI3K | GWAS association (p=5.0e-08) | Major Consortium Study |
| rs951266 | CHRNA5 | GWAS association (p=6.0e-14) | Major Consortium Study |
| rs602633 | — | GWAS association (p=4.0e-09) | Major Consortium Study |
| rs1556516 | CDKN2B-AS1 | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs1317286 | CHRNA3 | GWAS association (p=2.0e-31) | Major Consortium Study |
| rs769449 | APOE | GWAS association (p=2.0e-20) | Large GWAS |
| rs9457925 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs9457827 | — | GWAS association (p=7.0e-12) | Large GWAS |
| rs6224 | FURIN | GWAS association (p=1.0e-10) | Large GWAS |
| rs9872864 | — | GWAS association (p=7.0e-10) | Large GWAS |
| rs15285 | LPL | GWAS association (p=8.0e-10) | Large GWAS |
| rs4887072 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs6511720 | LDLR | GWAS association (p=3.0e-09) | Large GWAS |
| rs931794 | HYKK | GWAS association (p=3.0e-09) | Large GWAS |
| rs34967069 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs599839 | PSRC1 | GWAS association (p=4.0e-09) | Large GWAS |
| rs1275922 | — | GWAS association (p=6.0e-09) | Large GWAS |
| rs1230666 | MAGI3 | GWAS association (p=6.0e-09) | Large GWAS |
| rs61348208 | — | GWAS association (p=6.0e-09) | Large GWAS |
| rs142158911 | — | GWAS association (p=8.0e-09) | Large GWAS |
| rs12924886 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs10774625 | ATXN2 | GWAS association (p=1.0e-08) | Large GWAS |
| rs11633223 | CHRNB4 | GWAS association (p=4.0e-08) | Large GWAS |
| rs4774495 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs17685 | POR | GWAS association (p=5.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.