Trait
SNPs associated with Healthspan, Parental Longevity, Life Span Determination Trait
24 genetic variants across 13 genes have been associated with Healthspan, Parental Longevity, Life Span Determination Trait in published research. Key genes include APOE, ATXN2, DEF8.
Associated variants24 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs429358 | APOE | GWAS association (p=1.0e-126) | Large GWAS |
| rs10455872 | LPA | GWAS association (p=4.0e-30) | Large GWAS |
| rs35198068 | — | GWAS association (p=4.0e-28) | Large GWAS |
| rs12203592 | IRF4 | GWAS association (p=8.0e-26) | Large GWAS |
| rs8042849 | — | GWAS association (p=1.0e-24) | Large GWAS |
| rs7859727 | — | GWAS association (p=4.0e-18) | Large GWAS |
| rs34831921 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs1126809 | TYR | GWAS association (p=8.0e-13) | Large GWAS |
| rs7137828 | ATXN2 | GWAS association (p=5.0e-12) | Large GWAS |
| rs4268748 | DEF8 | GWAS association (p=7.0e-12) | Large GWAS |
| rs61905747 | ZW10 | GWAS association (p=4.0e-10) | Large GWAS |
| rs1230666 | MAGI3 | GWAS association (p=2.0e-09) | Large GWAS |
| rs6224 | FURIN | GWAS association (p=2.0e-09) | Large GWAS |
| rs6511720 | LDLR | GWAS association (p=4.0e-09) | Large GWAS |
| rs12830425 | — | GWAS association (p=8.0e-09) | Large GWAS |
| rs1159806 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs4783780 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs1275922 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs700635 | FLACC1 | GWAS association (p=2.0e-08) | Large GWAS |
| rs4970836 | PSRC1 | GWAS association (p=3.0e-08) | Large GWAS |
| rs61348208 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs2643826 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs17499404 | LINC02513 | GWAS association (p=4.0e-08) | Large GWAS |
| rs159428 | — | GWAS association (p=4.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.