rs1275985

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

systolic blood pressure

Koskeridis F et al. “Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.” Nature Communications 15(1):9827 (2024)

Allele C

OR 0.03

p 2.0e-65

N 1,212,859

Large GWAS

European

diastolic blood pressure, alcohol drinking

Feitosa MF et al. “Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.” Plos One 13(6):e0198166 (2018)

Allele T

OR —

p 3.0e-32

N 133,351

Large GWAS

multi-ancestry

stroke

Zhou W et al. “Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease.” Cell Genomics 2(10):100192 (2022)

Allele T

OR 0.04

p 1.0e-9

N 1,370,901

Meta-analysisLarge GWAS

multi-ancestry

QT interval

Young WJ et al. “Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.” Nature Communications 13(1):5144 (2022)

Allele T

OR 0.02

p 2.0e-9

N 212,199

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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