rs12967135
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (9)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (9)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
body weight
Tachmazidou I et al. “Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.” American Journal of Human Genetics 100(6):865-884 (2017)
Allele A
OR 0.07
p 1.0e-21
N 57,043
Large GWAS
European
cigarettes per day measurement
Koskeridis F et al. “Pleiotropic genetic architecture and novel loci for C-reactive protein levels.” Nature Communications 13(1):6939 (2022)
Allele A
OR 0.03
p 1.0e-19
N 337,334
Large GWAS
European
body mass index
Tachmazidou I et al. “Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.” American Journal of Human Genetics 100(6):865-884 (2017)
Allele A
OR 0.06
p 1.0e-16
N 56,793
Large GWAS
European
waist circumference
Tachmazidou I et al. “Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.” American Journal of Human Genetics 100(6):865-884 (2017)
Allele A
OR 0.05
p 3.0e-11
N 50,665
Large GWAS
European
hip circumference
Tachmazidou I et al. “Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.” American Journal of Human Genetics 100(6):865-884 (2017)
Allele A
OR 0.06
p 7.0e-11
N 37,078
Large GWAS
European
atrial fibrillation
Jordà P et al. “Genetic analyses across cardiovascular traits: leveraging genetic correlations to empower locus discovery and prediction in common cardiovascular diseases.” Npj Genomic Medicine 10(1):65 (2025)
Allele A
OR 6.37
p 2.0e-10
N 296,021
Large GWAS
European
C-reactive protein measurement, high density lipoprotein cholesterol measurement
Ligthart S et al. “Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.” Bmc Genomics 17:443 (2016)
Allele A
OR —
p 4.0e-10
N 164,900
Large GWAS
sex hormone-binding globulin measurement
Harrison S et al. “Testosterone and socioeconomic position: Mendelian randomization in 306,248 men and women in UK Biobank.” Science Advances 7(31) (2021)
Allele A
OR 0.54
p 6.0e-9
N 148,248
Major Consortium StudyLarge GWAS
European
high density lipoprotein cholesterol measurement
Teslovich TM et al. “Biological, clinical and population relevance of 95 loci for blood lipids.” Nature 466(7307):707-713 (2010)
Allele A
OR 0.42
p 7.0e-9
N 99,900
Large GWAS
European
Willer CJ et al. “Discovery and refinement of loci associated with lipid levels.” Nature Genetics 45(11):1274-1283 (2013)
Allele A
OR —
β 0.026
p 4.0e-8
N 94,595
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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