rs140244541

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

probable serine carboxypeptidase CPVL measurement

Allele A
OR 0.03
p 7.0e-15
N 47,745
Large GWAS
European

white matter integrity

Allele A
OR 0.08
p 2.0e-9
N 20,860
Major Consortium StudyLarge GWAS
European

low density lipoprotein cholesterol measurement

Surakka I et al. The impact of low-frequency and rare variants on lipid levels. Nature Genetics 47(6):589-97 (2015)
Allele G
OR 0.05
p 6.0e-9
N 62,166
Large GWAS
European

white matter integrity, age at assessment

Traylor M et al. The BS variant of C4 protects against age-related loss of white matter microstructural integrity. Brain : a Journal of Neurology 145(1):295-304 (2022)
Allele A
OR
p 4.0e-8
N 31,128
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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