rs1514895

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

glucose measurement

Allele A
OR 0.01
p 3.0e-121
N 475,416
Large GWAS
multi-ancestry
Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.04
p 5.0e-20
N 136,016
Large GWAS
multi-ancestry

type 2 diabetes mellitus

Allele A
OR
p 3.0e-48
N 2,535,601
Large GWAS
multi-ancestry
Allele A
OR 0.06
p 1.0e-24
N 6,710,881
Meta-analysisLarge GWAS
multi-ancestry

C-reactive protein measurement

Koskeridis F et al. Pleiotropic genetic architecture and novel loci for C-reactive protein levels. Nature Communications 13(1):6939 (2022)
Allele A
OR 0.02
p 4.0e-19
N 575,531
Large GWAS
European
Allele A
OR 0.03
p 3.0e-9
N 148,164
Large GWAS
European

HbA1c measurement

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.03
p 1.0e-19
N 492,283
Major Consortium StudyLarge GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…