rs1561277

GWAS Catalog Trait Associations (5)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

gut microbiome measurement

Allele A
OR 7.71
p 1.0e-14
N 18,340
Large GWAS
multi-ancestry

total cholesterol measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.02
p 2.0e-12
N 355,858
Major Consortium StudyLarge GWAS
multi-ancestry

morbid obesity

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.06
p 4.0e-11
N 611,383
Major Consortium StudyLarge GWAS
multi-ancestry

apolipoprotein A 1 measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.02
p 2.0e-9
N 323,833
Major Consortium StudyLarge GWAS
multi-ancestry

hip circumference

Allele A
OR 0.02
p 6.0e-9
N 143,480
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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