Trait
SNPs associated with Morbid Obesity
45 genetic variants across 17 genes have been associated with Morbid Obesity in published research. Key genes include AS3MT, DTX2P1-UPK3BP1-PMS2P11, FAIM2.
Associated variants45 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1421085 | FTO | GWAS association (p=1.0e-173) | Major Consortium Study |
| rs34872471 | TCF7L2 | GWAS association (p=5.0e-48) | Major Consortium Study |
| rs7903146 | TCF7L2 | GWAS association (p=6.0e-36) | Major Consortium Study |
| rs1800437 | GIPR | GWAS association (p=7.0e-27) | Major Consortium Study |
| rs13028310 | — | GWAS association (p=4.0e-26) | Major Consortium Study |
| rs10513801 | — | GWAS association (p=2.0e-25) | Major Consortium Study |
| rs12641981 | — | GWAS association (p=9.0e-25) | Major Consortium Study |
| rs2238691 | GIPR | GWAS association (p=1.0e-24) | Major Consortium Study |
| rs2820449 | — | GWAS association (p=2.0e-24) | Major Consortium Study |
| rs13107325 | SLC39A8 | GWAS association (p=1.0e-23) | Major Consortium Study |
| rs13387091 | — | GWAS association (p=2.0e-23) | Major Consortium Study |
| rs7132908 | FAIM2 | GWAS association (p=5.0e-22) | Major Consortium Study |
| rs2568952 | LOC105378797 | GWAS association (p=3.0e-21) | Major Consortium Study |
| rs6809651 | — | GWAS association (p=2.0e-20) | Major Consortium Study |
| rs6567160 | — | GWAS association (p=7.0e-19) | Major Consortium Study |
| rs12883788 | — | GWAS association (p=3.0e-18) | Major Consortium Study |
| rs2943647 | — | GWAS association (p=1.0e-17) | Major Consortium Study |
| rs879620 | — | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs4776970 | MAP2K5 | GWAS association (p=8.0e-17) | Major Consortium Study |
| rs58862095 | POM121C | GWAS association (p=3.0e-16) | Major Consortium Study |
| rs478788 | — | GWAS association (p=3.0e-16) | Major Consortium Study |
| rs59770119 | — | GWAS association (p=3.0e-16) | Major Consortium Study |
| rs34517439 | — | GWAS association (p=2.0e-15) | Major Consortium Study |
| rs62405422 | TFAP2B | GWAS association (p=3.0e-15) | Major Consortium Study |
| rs11642015 | FTO | GWAS association (p=1.0e-14) | Major Consortium Study |
| rs160329 | MCM6 | GWAS association (p=4.0e-14) | Major Consortium Study |
| rs261966 | — | GWAS association (p=3.0e-13) | Major Consortium Study |
| rs751414 | — | GWAS association (p=4.0e-13) | Major Consortium Study |
| rs17770163 | LINGO2 | GWAS association (p=4.0e-13) | Major Consortium Study |
| rs45486197 | — | GWAS association (p=5.0e-13) | Major Consortium Study |
| rs56010427 | DTX2P1-UPK3BP1-PMS2P11 | GWAS association (p=6.0e-13) | Major Consortium Study |
| rs4923464 | — | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs7925389 | — | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs58857776 | LINC01122 | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs1801282 | PPARG | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs10510554 | — | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs10983719 | — | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs2410767 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs11012726 | — | GWAS association (p=5.0e-12) | Major Consortium Study |
| rs9380823 | — | GWAS association (p=5.0e-12) | Major Consortium Study |
| rs17878846 | AS3MT | GWAS association (p=6.0e-12) | Major Consortium Study |
| rs371918919 | SH2B1 | GWAS association (p=8.0e-12) | Major Consortium Study |
| rs321252 | LINC02790 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs1561277 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs1558902 | FTO | GWAS association (p=7.0e-122) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.