rs6809651
▶GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
overnutrition, obesity
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.07
p 7.0e-29
N 575,115
Major Consortium StudyLarge GWAS
multi-ancestry
morbid obesity
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.09
p 2.0e-20
N 611,383
Major Consortium StudyLarge GWAS
multi-ancestry
interleukin-27 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.06
p 2.0e-18
N 47,745
Large GWAS
European
physical activity measurement, body mass index
Graff M et al. “Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.” Plos Genetics 13(4):e1006528 (2017)
Allele G
OR 0.05
p 3.0e-17
N 161,368
Meta-analysisLarge GWAS
multi-ancestry
osteoarthritis, hip, osteoarthritis, knee
Hatzikotoulas K et al. “Translational genomics of osteoarthritis in 1,962,069 individuals.” Nature 641(8065):1217-1224 (2025)
Allele A
OR 0.97
p 1.0e-8
N 1,294,321
Large GWAS
multi-ancestry
serum creatinine amount, glomerular filtration rate
Gorski M et al. “1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.” Scientific Reports 7:45040 (2017)
Allele A
OR 0.01
p 2.0e-8
N 110,517
Meta-analysisLarge GWAS
European
glomerular filtration rate
Morris AP et al. “Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.” Nature Communications 10(1):29 (2019)
Allele A
OR —
β 0.299
p 3.0e-8
N 312,296
Large GWAS
multi-ancestry
body mass index
Graff M et al. “Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.” Plos Genetics 13(4):e1006528 (2017)
Allele G
OR 0.05
p 1.0e-10
N 123,097
Meta-analysisLarge GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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