rs17024393

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GWAS Catalog Trait Associations (9)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body mass index

Pulit SL et al. “Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.” Human Molecular Genetics 28(1):166-174 (2019)

Allele T

OR 0.06

p 7.0e-39

N 806,834

Meta-analysisLarge GWAS

European

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)

Allele T

OR 0.06

p 7.0e-18

N 523,818

Large GWAS

multi-ancestry

Hoffmann TJ et al. “A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.” Genetics 210(2):499-515 (2018)

Allele T

OR —

β 0.053

p 6.0e-13

N 334,487

Large GWAS

multi-ancestry

Locke AE et al. “Genetic studies of body mass index yield new insights for obesity biology.” Nature 518(7538):197-206 (2015)

Allele T

OR 0.07

p 7.0e-14

N 238,944

Large GWAS

multi-ancestry

Justice AE et al. “Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.” Nature Communications 8:14977 (2017)

Allele T

OR 0.06

p 1.0e-9

N 153,041

Meta-analysisLarge GWAS

multi-ancestry

Graff M et al. “Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.” Plos Genetics 13(4):e1006528 (2017)

Allele T

OR 0.09

p 2.0e-9

N 123,097

Meta-analysisLarge GWAS

multi-ancestry

Felix JF et al. “Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.” Human Molecular Genetics 25(2):389-403 (2016)

Allele T

OR —

p 3.0e-8

N 34,744

Large GWAS

European

body weight

Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)

Allele T

OR 0.08

p 2.0e-26

N 928,679

Large GWAS

multi-ancestry

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)

Allele T

OR 0.05

p 4.0e-17

N 525,535

Large GWAS

multi-ancestry

fat pad mass

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele C

OR 0.06

p 1.0e-21

N 394,642

Large GWAS

European

Harris BHL et al. “New role of fat-free mass in cancer risk linked with genetic predisposition.” Scientific Reports 14(1):7270 (2024)

Allele C

OR 0.06

p 7.0e-17

N 337,196

Large GWAS

European

physical activity measurement, body mass index

Graff M et al. “Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.” Plos Genetics 13(4):e1006528 (2017)

Allele C

OR 0.08

p 2.0e-15

N 161,368

Meta-analysisLarge GWAS

multi-ancestry

C-reactive protein measurement

Koskeridis F et al. “Pleiotropic genetic architecture and novel loci for C-reactive protein levels.” Nature Communications 13(1):6939 (2022)

Allele T

OR 0.04

p 2.0e-11

N 575,531

Large GWAS

European

non-alcoholic fatty liver disease

Du M et al. “Cross-trait genomic modeling reveals the polygenic architecture and systemic impact of MASLD.” Science Advances 12(7):eaeb5665 (2026)

Allele T

OR 0.08

p 6.0e-11

N 122,644

Large GWAS

European

grip strength measurement

Tikkanen E et al. “Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.” Scientific Reports 8(1):6451 (2018)

Allele T

OR 0.01

p 2.0e-8

N 334,825

Major Consortium StudyLarge GWAS

European

hip circumference

Shungin D et al. “New genetic loci link adipose and insulin biology to body fat distribution.” Nature 518(7538):187-196 (2015)

Allele T

OR 0.06

p 3.0e-10

N 143,480

Large GWAS

multi-ancestry

smoking behavior, body mass index

Justice AE et al. “Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.” Nature Communications 8:14977 (2017)

Allele T

OR —

p 2.0e-11

N 196,760

Meta-analysisLarge GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

rs17024393

GWAS Catalog Trait Associations (9)

body mass index

body weight

fat pad mass

physical activity measurement, body mass index

C-reactive protein measurement

non-alcoholic fatty liver disease

grip strength measurement

hip circumference

smoking behavior, body mass index

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