rs17111503

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GWAS Catalog Trait Associations (7)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

proprotein convertase subtilisin/kexin type 9 measurement

Pott J et al. “Meta-GWAS of PCSK9 levels detects two novel loci at APOB and TM6SF2.” Human Molecular Genetics 31(6):999-1011 (2022)
Allele G
OR 0.04
p 8.0e-15
N 12,721
Large GWAS
European

low density lipoprotein cholesterol measurement

Koskeridis F et al. “Pleiotropic genetic architecture and novel loci for C-reactive protein levels.” Nature Communications 13(1):6939 (2022)
Allele A
OR 0.01
p 7.0e-9
N 361,194
Large GWAS
European
Hoffmann TJ et al. “A large electronic-health-record-based genome-wide study of serum lipids.” Nature Genetics 50(3):401-413 (2018)
Allele A
OR —
β 0.053
p 6.0e-20
N 94,674
Large GWAS
multi-ancestry

total cholesterol measurement

Hoffmann TJ et al. “A large electronic-health-record-based genome-wide study of serum lipids.” Nature Genetics 50(3):401-413 (2018)
Allele A
OR —
β 0.049
p 5.0e-18
N 94,674
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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