rs2212434
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
atopic eczema
Chen Y et al. “Genome-Wide Integration of Genetic and Genomic Studies of Atopic Dermatitis: Insights into Genetic Architecture and Pathogenesis.” The Journal of Investigative Dermatology 142(11):2958-2967.e8 (2022)
Allele T
OR 0.08
p 8.0e-21
N 837,496
Large GWAS
multi-ancestry
Paternoster L et al. “Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.” Nature Genetics 47(12):1449-1456 (2015)
Allele T
OR 1.09
p 5.0e-13
N 116,863
Large GWAS
multi-ancestry
basal cell carcinoma
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.07
p 1.0e-14
N 435,548
Major Consortium StudyLarge GWAS
European
food allergy measurement
Marenholz I et al. “Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy.” Nature Communications 8(1):1056 (2017)
Allele T
OR 1.29
p 9.0e-11
N 2,884
Large GWAS
European
psoriasis
Dand N et al. “GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets.” Nature Communications 16(1):2051 (2025)
Allele T
OR 1.05
p 3.0e-8
N 494,544
Meta-analysisLarge GWAS
European
type 1 diabetes mellitus
Crouch DJM et al. “Bayesian Effect Size Ranking to Prioritise Genetic Risk Variants in Common Diseases for Follow-Up Studies.” Genetic Epidemiology 49(1):e22608 (2025)
Allele T
OR 1.08
p 4.0e-8
N 173,981
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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