rs2398144

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GWAS Catalog Trait Associations (6)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

chronotype measurement

Jansen PR et al. “Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.” Nature Genetics 51(3):394-403 (2019)
Allele A
OR 0.02
p 2.0e-21
N 434,835
Large GWAS
European

insomnia

Watanabe K et al. “Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.” Nature Genetics 54(8):1125-1132 (2022)
Allele A
OR 0.01
p 9.0e-20
N 2,365,010
Meta-analysisLarge GWAS
European

insomnia measurement

Jansen PR et al. “Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.” Nature Genetics 51(3):394-403 (2019)
Allele A
OR 1.04
p 5.0e-10
N 1,331,010
Large GWAS
European

neuroticism measurement

Turley P et al. “Multi-trait analysis of genome-wide association summary statistics using MTAG.” Nature Genetics 50(2):229-237 (2018)
Allele A
OR 0.02
p 1.0e-8
N 168,105
Large GWAS
European

depressive symptom measurement

Turley P et al. “Multi-trait analysis of genome-wide association summary statistics using MTAG.” Nature Genetics 50(2):229-237 (2018)
Allele A
OR 0.01
p 2.0e-8
N 354,862
Large GWAS
European

wellbeing measurement

Turley P et al. “Multi-trait analysis of genome-wide association summary statistics using MTAG.” Nature Genetics 50(2):229-237 (2018)
Allele A
OR 0.01
p 1.0e-8
N 388,538
Large GWAS
European
Baselmans BML et al. “Multivariate genome-wide analyses of the well-being spectrum.” Nature Genetics 51(3):445-451 (2019)
Allele A
OR 0.01
p 2.0e-10
N 80,852
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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