rs2431098
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
systemic lupus erythematosus
Bentham J et al. “Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.” Nature Genetics 47(12):1457-1464 (2015)
Allele G
OR 1.25
p 4.0e-18
N 14,267
Large GWAS
European
systemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus
Acosta-Herrera M et al. “Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.” Annals of the Rheumatic Diseases 78(3):311-319 (2019)
Allele G
OR 1.12
p 5.0e-12
N 31,408
Meta-analysisLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…