Trait
SNPs associated with Systemic Scleroderma, Rheumatoid Arthritis, Myositis, Systemic Lupus Erythematosus
17 genetic variants across 7 genes have been associated with Systemic Scleroderma, Rheumatoid Arthritis, Myositis, Systemic Lupus Erythematosus in published research. Key genes include DNASE1L3, IRF5, NCF2.
Associated variants17 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs13238352 | TNPO3 | GWAS association (p=1.0e-38) | Meta-analysis |
| rs6679677 | PHTF1 | GWAS association (p=2.0e-28) | Meta-analysis |
| rs58721818 | — | GWAS association (p=5.0e-23) | Meta-analysis |
| rs2736337 | — | GWAS association (p=5.0e-22) | Meta-analysis |
| rs13389408 | — | GWAS association (p=3.0e-17) | Meta-analysis |
| rs10954214 | IRF5 | GWAS association (p=7.0e-17) | Meta-analysis |
| rs17849502 | NCF2 | GWAS association (p=4.0e-15) | Meta-analysis |
| rs5754467 | — | GWAS association (p=1.0e-13) | Meta-analysis |
| rs2431098 | — | GWAS association (p=5.0e-12) | Meta-analysis |
| rs4958880 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs193107685 | — | GWAS association (p=3.0e-09) | Meta-analysis |
| rs35677470 | DNASE1L3 | GWAS association (p=5.0e-09) | Meta-analysis |
| rs112846137 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs13101828 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs2422345 | TNFSF4 | GWAS association (p=3.0e-08) | Meta-analysis |
| rs76246107 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs11066301 | PTPN11 | GWAS association (p=4.0e-08) | Meta-analysis |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.