rs2548957
▶GWAS Catalog Trait Associations (9)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (9)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
alkaline phosphatase measurement
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.04
p 1.0e-74
N 355,891
Major Consortium StudyLarge GWAS
multi-ancestry
fibroblast growth factor 21 level
Larsson SC et al. “Genome-wide association and Mendelian randomization study of fibroblast growth factor 21 reveals causal associations with hyperlipidemia and possibly NASH.” Metabolism: Clinical and Experimental 137:155329 (2022)
Allele A
OR 0.18
p 2.0e-42
N 6,259
Large GWAS
European
total cholesterol measurement
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.02
p 9.0e-14
N 355,858
Major Consortium StudyLarge GWAS
multi-ancestry
low density lipoprotein cholesterol measurement
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.02
p 2.0e-12
N 355,197
Major Consortium StudyLarge GWAS
multi-ancestry
serum gamma-glutamyl transferase measurement
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.02
p 3.0e-11
N 355,690
Major Consortium StudyLarge GWAS
multi-ancestry
apolipoprotein B measurement
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.02
p 8.0e-11
N 354,097
Major Consortium StudyLarge GWAS
multi-ancestry
level of serum globulin type protein
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.02
p 5.0e-10
N 325,292
Major Consortium StudyLarge GWAS
multi-ancestry
serum urea amount
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.01
p 2.0e-9
N 355,637
Major Consortium StudyLarge GWAS
multi-ancestry
milk amount
Ambalavanan A et al. “Human milk oligosaccharides are associated with maternal genetics and respiratory health of human milk-fed children.” Nature Communications 15(1):7735 (2024)
Allele A
OR 6.91
p 5.0e-12
N 980
Small GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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