rs2906184

This is a downstream gene variant variant in the BRI3 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

gout

Major TJ et al. “A genome-wide association analysis reveals new pathogenic pathways in gout.” Nature Genetics 56(11):2392-2406 (2024)

Allele A

OR 0.94

p 2.0e-14

N 1,011,521

Large GWAS

European

low density lipoprotein cholesterol measurement

Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)

Allele A

OR 0.03

p 2.0e-13

N 153,950

Large GWAS

East Asian

About BRI3

Enables identical protein binding activity. Predicted to be located in azurophil granule membrane and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all BRI3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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