rs30351

This is a intergenic variant variant.

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GWAS Catalog Trait Associations (9)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

triglyceride measurement

Martin S et al. “Genetic Evidence for Different Adiposity Phenotypes and Their Opposing Influences on Ectopic Fat and Risk of Cardiometabolic Disease.” Diabetes 70(8):1843-1856 (2021)
Allele G
OR —
β 0.031
p 9.0e-44
N 429,011
Large GWAS
European
Lind L et al. “Genetic Determinants of Clustering of Cardiometabolic Risk Factors in U.K. Biobank.” Metabolic Syndrome and Related Disorders 18(3):121-127 (2020)
Allele G
OR 0.02
p 7.0e-21
N 291,107
Large GWAS
European

high density lipoprotein cholesterol measurement

Martin S et al. “Genetic Evidence for Different Adiposity Phenotypes and Their Opposing Influences on Ectopic Fat and Risk of Cardiometabolic Disease.” Diabetes 70(8):1843-1856 (2021)
Allele G
OR —
β 0.027
p 2.0e-38
N 392,965
Large GWAS
European
Lind L et al. “Genetic Determinants of Clustering of Cardiometabolic Risk Factors in U.K. Biobank.” Metabolic Syndrome and Related Disorders 18(3):121-127 (2020)
Allele G
OR 0.01
p 2.0e-17
N 291,107
Large GWAS
European

body fat percentage

Martin S et al. “Genetic Evidence for Different Adiposity Phenotypes and Their Opposing Influences on Ectopic Fat and Risk of Cardiometabolic Disease.” Diabetes 70(8):1843-1856 (2021)
Allele G
OR —
β 0.012
p 2.0e-12
N 442,278
Large GWAS
European

visceral:gluteofemoral adipose tissue ratio measurement

Agrawal S et al. “Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots.” Nature Communications 13(1):3771 (2022)
Allele G
OR 0.07
p 4.0e-9
N 18,984
Large GWAS
European, East Asian, South Asian, African unspecified, NR

pericardial fat amount

Rämö JT et al. “Cardiovascular Significance and Genetics of Epicardial and Pericardial Adiposity.” Jama Cardiology 9(5):418-427 (2024)
Allele A
OR 0.46
p 2.0e-8
N 44,356
CohortLarge GWAS
multi-ancestry

visceral adipose tissue quantity

Agrawal S et al. “Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots.” Nature Communications 13(1):3771 (2022)
Allele G
OR 0.09
p 4.0e-13
N 18,368
Large GWAS
European, East Asian, South Asian, African unspecified, NR

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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