rs35102600

This is a intron variant variant in the SEC14L6 gene.

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

free cholesterol to total lipids in medium HDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 6.0e-15
N 450,015
Large GWAS
multi-ancestry

HDL cholesterol change measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 3.0e-14
N 450,015
Large GWAS
multi-ancestry

free cholesterol in HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.01
p 2.0e-13
N 450,015
Large GWAS
multi-ancestry

About SEC14L6

Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all SEC14L6 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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