rs35412

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

skin sensitivity to sun

Farré X et al. “Skin Phototype and Disease: A Comprehensive Genetic Approach to Pigmentary Traits Pleiotropy Using PRS in the GCAT Cohort.” Genes 14(1) (2023)

Allele C

OR 0.54

p 6.0e-36

N 4,985

Large GWAS

European

freckles

Farré X et al. “Skin Phototype and Disease: A Comprehensive Genetic Approach to Pigmentary Traits Pleiotropy Using PRS in the GCAT Cohort.” Genes 14(1) (2023)

Allele C

OR 0.24

p 5.0e-9

N 4,984

Large GWAS

European

Abnormality of skin pigmentation

Liu F et al. “Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up.” Human Genetics 134(8):823-35 (2015)

Allele C

OR 0.20

p 3.0e-8

N 9,316

Large GWAS

European

skin pigmentation

Farré X et al. “Skin Phototype and Disease: A Comprehensive Genetic Approach to Pigmentary Traits Pleiotropy Using PRS in the GCAT Cohort.” Genes 14(1) (2023)

Allele C

OR 0.48

p 3.0e-75

N 4,985

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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