rs35665085

GWAS Catalog Trait Associations (8)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

alanine measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.04
p 7.0e-21
N 450,015
Large GWAS
multi-ancestry

body height

Allele A
OR 0.02
p 2.0e-14
N 394,642
Large GWAS
European
Allele A
OR 0.02
p 5.0e-12
N 405,540
Large GWAS
European

triglyceride measurement

Liu DJ et al. Exome-wide association study of plasma lipids in >300,000 individuals. Nature Genetics 49(12):1758-1766 (2017)
Allele A
OR 0.03
p 3.0e-14
N 297,824
Large GWAS
multi-ancestry
Allele A
OR 0.02
p 9.0e-10
N 1,320,016
Large GWAS
European

total lipids in small HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.03
p 2.0e-12
N 450,015
Large GWAS
multi-ancestry

alkaline phosphatase measurement

Allele A
OR 0.03
p 1.0e-11
N 394,642
Large GWAS
European

phospholipids in small HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.03
p 2.0e-11
N 450,015
Large GWAS
multi-ancestry

concentration of small HDL particles measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.03
p 3.0e-11
N 450,015
Large GWAS
multi-ancestry

cholesterol in small HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.03
p 9.0e-11
N 450,015
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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