rs35739466

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

high density lipoprotein cholesterol measurement

Koskeridis F et al. Pleiotropic genetic architecture and novel loci for C-reactive protein levels. Nature Communications 13(1):6939 (2022)
Allele A
OR 0.11
p 2.0e-310
N 361,194
Large GWAS
European

cholesterol:total lipids ratio, blood VLDL cholesterol amount

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.07
p 8.0e-60
N 136,016
Large GWAS
multi-ancestry

cholesteryl esters:total lipids ratio, blood VLDL cholesterol amount

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.06
p 4.0e-43
N 136,016
Large GWAS
multi-ancestry

metabolic syndrome

Allele G
OR 0.16
p 4.0e-32
N 107,230
Large GWAS
East Asian

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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