rs40465
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
major depressive disorder
Als TD et al. “Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses.” Nature Medicine 29(7):1832-1844 (2023)
Allele T
OR 0.03
p 3.0e-20
N 1,349,887
Large GWAS
European
Howard DM et al. “Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.” Nature Communications 9(1):1470 (2018)
Allele T
OR 0.01
p 4.0e-10
N 322,580
Major Consortium StudyLarge GWAS
European
sexual activity behaviour attribute
Karlsson Linnér R et al. “Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.” Nature Genetics 51(2):245-257 (2019)
Allele T
OR 0.02
p 7.0e-14
N 370,711
Large GWAS
European
sodium measurement
Pazoki R et al. “GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits.” Nature Communications 10(1):3653 (2019)
Allele T
OR 0.01
p 3.0e-10
N 446,237
Large GWAS
multi-ancestry
chronotype measurement
Jansen PR et al. “Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.” Nature Genetics 51(3):394-403 (2019)
Allele T
OR 0.01
p 2.0e-8
N 434,835
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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