rs4360309
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
total cholesterol measurement
Hoffmann TJ et al. “A large electronic-health-record-based genome-wide study of serum lipids.” Nature Genetics 50(3):401-413 (2018)
Allele C
OR —
β 0.035
p 1.0e-14
N 94,674
Large GWAS
multi-ancestry
basophil percentage of leukocytes
Astle WJ et al. “The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.” Cell 167(5):1415-1429.e19 (2016)
Allele T
OR 0.02
p 1.0e-10
N 171,996
Large GWAS
European
basophil percentage of granulocytes
Astle WJ et al. “The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.” Cell 167(5):1415-1429.e19 (2016)
Allele T
OR 0.02
p 2.0e-9
N 170,223
Large GWAS
European
low density lipoprotein cholesterol measurement
Hoffmann TJ et al. “A large electronic-health-record-based genome-wide study of serum lipids.” Nature Genetics 50(3):401-413 (2018)
Allele C
OR —
β 0.031
p 5.0e-10
N 94,674
Large GWAS
multi-ancestry
triglyceride measurement
Hoffmann TJ et al. “A large electronic-health-record-based genome-wide study of serum lipids.” Nature Genetics 50(3):401-413 (2018)
Allele C
OR —
β 0.038
p 2.0e-18
N 94,674
Large GWAS
multi-ancestry
Ko A et al. “Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.” Nature Communications 5:3983 (2014)
Allele C
OR 1.35
p 7.0e-9
N 3,323
Large GWAS
Hispanic or Latin American
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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